I've never been comfortable around people that enjoy drinking. There's a wide variety of ways people express their drunkenness. Most people I know laugh a lot, or get really loud. And honestly, I don't care if friends of mine drink while we're hanging out, or over dinner. It's common in most countries to drink with dinner. That doesn't bother me.
I suppose what bothers me is the extreme spectrum moods can be. Then how everyone else must deal with said person. Certainly, when I've been in such situations, I vacate asap. I mean, if you're uncomfortable, the automatic response is to take flight.